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Medications that inhibit CYP2D6 activity, like paroxetine and quinidine, may perhaps cause decreased clearance of oxycodone which may lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in an increase in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.Keep an index of all the products you use (which in